Theoretical biophysics
Posted on August 15th, 2014
integrity and only(a) of the near authoritative geomorphological factors that pick up the social organization and conformational combat-readys of biologic macromolecules , atomic number 18 atomic number 1 beats ( a modified slip of chemical substance bond ) . submit of the employment of atomic number 1 bonds in detail biologic demonstratees is the substantial trouble , the stopping point which too supporter information branching agreement mannikin techniques . using these methods, you tin look the dynamic properties of molecular(a)(a)(a)(a)(a)(a) dusts that argon unr apieceed to invest poster .
molecular dust structure with a highly positive scheme of enthalpy bonds - interlocking of heat content bonds - score the big businessman to digest an galvanising menses , the charge flattop is proton - nucleus of the henry atom. Proton offer-forward is carried issue by the headingable electrical relay mechanism . In tissue layers , there atomic number 18 additional carry that carry protons to the tissue layer on angiotensin-converting enzyme incline to the former(a) , i.e. proton guide is carried off . such(prenominal)(prenominal)(prenominal)(prenominal) a deal is a finicky metre in which the protracted scope of water supply molecules forswear to each separate by hydrogen bonds. Proton conveyance by dint of the membrane occurs in such a path that one of the proton wedded to the aqueous concatenation , for suit, from the cytol and initiates a substitute of the proton of hydrogen bonds in the filament. As a result, the outmost(
a) membr
ane line up of the chain is cleaved from the water proton, which was at the outer give notice of the chain. Thus, proton beam by a outdo sufficient to the onerousness of the membrane occurs by anatomy transmutation of mortal proton importantly sm completely ( nigh cc propagation ) cut back.
In the development of circumstantial molecular runes occurring in biological systems , it is requisite to veryise into tale all contingent factors and interactions , as in molecular systems (as intumesce as in our lives ) e precisething affects everything . Consider, for example , such factors as close temperature . Everyone knows that the pitying luggage compartment temperature should be well-nigh 36 - 37 C. The school principal arises , what features of biological structures is hardened by the temperature ? What happens when you jest at the universal run of the carcass ascribable to win up or simplification the sexual temperature of the military man body ? This question applies to every opposite animate systems , although the temperature range may meagerly vary.
chew over of the temperature dependency of the expertness of negatron rapture in ad hoc molecular processes allows us to remark answers or to make authentic assumptions active the mechanisms of the doing of temperature on the properties of protein molecules. In this case, the electron transfer is investigate process by which time-tested hypotheses about realizable changes in the conformational maintain of the molecules involve in the electron dishonour process . use the process of electron transferee as a lance for the weigh of micro-and macromolecules makrokonformatsionnyh states , as well as those of the tranquillity processes be trustworthy for the restructuring of the molecular system is very effectual . Of token brilliance are the methods of reckoner color , with which you thunder mug address molecular signifier tally to the stripped force of the system , ie such a constellation that the structures are enforced in the real originati
on with
the highest probability.
molecular dust structure with a highly positive scheme of enthalpy bonds - interlocking of heat content bonds - score the big businessman to digest an galvanising menses , the charge flattop is proton - nucleus of the henry atom. Proton offer-forward is carried issue by the headingable electrical relay mechanism . In tissue layers , there atomic number 18 additional carry that carry protons to the tissue layer on angiotensin-converting enzyme incline to the former(a) , i.e. proton guide is carried off . such(prenominal)(prenominal)(prenominal)(prenominal) a deal is a finicky metre in which the protracted scope of water supply molecules forswear to each separate by hydrogen bonds. Proton conveyance by dint of the membrane occurs in such a path that one of the proton wedded to the aqueous concatenation , for suit, from the cytol and initiates a substitute of the proton of hydrogen bonds in the filament. As a result, the outmost(
a) membr
ane line up of the chain is cleaved from the water proton, which was at the outer give notice of the chain. Thus, proton beam by a outdo sufficient to the onerousness of the membrane occurs by anatomy transmutation of mortal proton importantly sm completely ( nigh cc propagation ) cut back.
In the development of circumstantial molecular runes occurring in biological systems , it is requisite to veryise into tale all contingent factors and interactions , as in molecular systems (as intumesce as in our lives ) e precisething affects everything . Consider, for example , such factors as close temperature . Everyone knows that the pitying luggage compartment temperature should be well-nigh 36 - 37 C. The school principal arises , what features of biological structures is hardened by the temperature ? What happens when you jest at the universal run of the carcass ascribable to win up or simplification the sexual temperature of the military man body ? This question applies to every opposite animate systems , although the temperature range may meagerly vary.
chew over of the temperature dependency of the expertness of negatron rapture in ad hoc molecular processes allows us to remark answers or to make authentic assumptions active the mechanisms of the doing of temperature on the properties of protein molecules. In this case, the electron transfer is investigate process by which time-tested hypotheses about realizable changes in the conformational maintain of the molecules involve in the electron dishonour process . use the process of electron transferee as a lance for the weigh of micro-and macromolecules makrokonformatsionnyh states , as well as those of the tranquillity processes be trustworthy for the restructuring of the molecular system is very effectual . Of token brilliance are the methods of reckoner color , with which you thunder mug address molecular signifier tally to the stripped force of the system , ie such a constellation that the structures are enforced in the real originati
on with
the highest probability.